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Sanjay Kalra

Sanjay Kalra

Bharti Research Institute of Diabetes & Endocrinology, India

Title: Medical nutritional supplement improves glycemic control in type 2 diabetes and prediabetes: A prospective study in Indian population

Biography

Biography: Sanjay Kalra

Abstract

Aim: To determine the long-term effect of Medical Nutrition Therapy (MNT) in adults with type 2 diabetes (T2D) and prediabetes. 
 
Background: T2D is one of the major non-communicable diseases with increasing prevalence at a global level. Individuals with T2D are at high risk of developing cardiovascular and other life-threatening conditions. Nutrient intake imbalances in diabetics are also frequently present due to food restrictions. Therefore, the effect of MNT in diabetic and pre-diabetics is studied for 24 weeks. 
 
Methods: This is a prospective observational study where MNT (VidavanceTM) is given for 24 weeks to 325 adult participants with T2D or prediabetes (HbA1c >6.0). Participants were either taking anti-diabetic therapies along with MNT (n=156), or MNT alone (n=158). Glucose metabolism parameters and lipid profile is assessed at baseline, 12 and 24 weeks.
 
Results: Total 313 participants completed the study. Statistically significant reduction in HbA1c levels is seen from baseline to 12 weeks (8.6 to 7.7; p<0.001) and 24 weeks (8.6 to 7.1: p<0.001), due to only MNT. Similar significant reduction in fasting glucose (167.4 to 119.4 mg/dL) and post-prandial glucose (232.1 to 156.2 mg/ dL) are observed at 24 weeks, due to only MNT. Significant reduction in levels of lipid profile parameters is also seen. No adverse event is observed.
 
Discussion: Overall, MNT is found to be efficacious in reducing hyperglycemic parameters. HbA1c is reduced by 0.9% at 12 weeks and by 1.5% at 24 weeks, due to only MNT. Significant reduction in fasting and post-prandial glucose is also seen.